NOVEL POLYPEPTIDES AND POLYNUCLEOTIDES ENCODING SAME

• Main Authors: PRAYAGA, SUDHIRDAS, K, SHIMKETS, RICHARD, A
• Format: Patent
• Language: English; French
• Published: 29.11.2001
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The invention provides polypeptides, designated herein as NOV polypeptides, as well as polynucleotides encoding NOV polypeptides, and antibodies that immunospecifically-bind to NOV polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the NOV polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states. L'invention concerne des polypeptides désignés polypeptides NOV, ainsi que des polynucléotides codant ces polypeptides NOV, des anticorps se fixant de façon immunospécifique à ce polypeptide NOV ou à ce polynucléotide, ou leurs dérivés, variantes ou mutants ou fragments. Elles concernent, de plus, des procédés, consistant à utiliser le polypeptide NOV, le polynucléotide et l'anticorps de ce dernier afin de détecter, de prévenir et de traiter une variété importante d'états pathologiques.