SERINE/THREONINE KINASE AND SERINE PROTEASE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING SAME

• Main Authors: FERNANDES, ELMA, TAUPIER, RAYMOND, JR, BURGESS, CATHERINE, QUINN, KERRY, E, RASTELLI, LUCA, SPYTEK, KIMBERLEY, ANN, MAJUMDER, KUMUD, HERRMANN, JOHN, L, VERNET, CORINE
• Format: Patent
• Language: English; French
• Published: 06.06.2002
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present invention provides novel isolated SERX polynucleotides and polypeptides encoded by the SERX polynucleotides. Also provided are the antibodies that immunospecifically bind to a SERX polypeptide or any derivative, variant, mutant or fragment of the SERX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SERX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses. L'invention concerne de nouveaux polynucléotides SERX isolés et des polypeptides codés par ces polynucléotides SERX. L'invention concerne également des anticorps qui lient de manière immunospécifique à un polypeptide SERX ou tout dérivé, variant, mutant ou fragment de ce polypeptide, polynucléotide ou anticorps SERX. La présente invention fait également état de procédés dans lesquels les polypeptides, polynucléotides et anticorps SERX sont utilisés afin de détecter et traiter une large gamme d'états pathologiques ainsi que d'autres utilisations.