CYTOCHROME P450 OXYGENASES AND THEIR USES

Oxygenase enzymes and the use of such enzymes to produce paclitaxel (Taxol), related taxoids, as well as intermediates in the Taxol biosynthetic pathway are disclosed. Also disclosed are nucleic acid sequences encoding the oxygenase enzymes. La présente invention concerne des enzymes oxygénases et l...

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Bibliographic Details
Main Authors JENNEWEIN, STEFAN, SCHOENDORF, ANNE, CROTEAU, RODNEY, B
Format Patent
LanguageEnglish
French
Published 08.11.2001
Edition7
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Summary:Oxygenase enzymes and the use of such enzymes to produce paclitaxel (Taxol), related taxoids, as well as intermediates in the Taxol biosynthetic pathway are disclosed. Also disclosed are nucleic acid sequences encoding the oxygenase enzymes. La présente invention concerne des enzymes oxygénases et leur utilisation pour produire du paclitaxel (Taxol), les taxoïdes associés, ainsi que des intermédiaires intervenant dans la voie de synthèse biologique du Taxol. Cette invention concerne également des séquences d'acide nucléique codant pour ces enzymes oxygénases.
Bibliography:Application Number: WO2000US31254