THIAZOLIDINEDIONE DERIVATIVES

Thiazolidinedione derivatives of the general formula (I) or pharmacologically acceptable salts thereof, exhibiting a telomerase-inhibiting effect, wherein R and R are each hydrogen, lower alkyl, or the like; r and r are each a single or double bond; and X is a group of the general formula (II) [wher...

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Main Authors SASHO, SETSUYA, AKAMA, TSUTOMU, ASAI, AKIRA, YAMASHITA, YOSHINORI, MURAKATA, CHIKARA, KITAMURA, YUSHI, KOBAYASHI, YUMIKO, KISHIKAWA, KUNIYUKI, KOMATSU, KAZUNORI, KANDA, YUTAKA
Format Patent
LanguageEnglish
French
Japanese
Published 03.05.2001
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Thiazolidinedione derivatives of the general formula (I) or pharmacologically acceptable salts thereof, exhibiting a telomerase-inhibiting effect, wherein R and R are each hydrogen, lower alkyl, or the like; r and r are each a single or double bond; and X is a group of the general formula (II) [wherein Y is NR (wherein R is hydrogen, lower alkyl, or the like) or the like] or the like.. L'invention concerne des dérivés de thiazolidinédione de formule générale (I), ou des sels de ceux-ci pharmaceutiquement acceptables, qui présentent un effet inhibant la télomérase. R et R représentent chacun hydrogène, alkyle faible, ou analogue; r et r représentent chacun une liaison simple ou double; et X représente un groupe de formule générale (II), [dans laquelle Y représente NR (R représentant hydrogène, ou analogue) ou analogue] ou analogue.
Bibliography:Application Number: WO2000JP07584