THE USE OF HUMAN FGH-8 POLYPEPTIDES AS NEUROTROPHIC AGENTS

The present invention relates to pharmaceutical compositions and methods of treating neurological disorders. Compositions of the present invention comprise at least one hFGF-8 polypeptide, or at least one isolated nucleic acid, or its complement, encoding at least one hFGF-8 polypeptide. The present...

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Bibliographic Details
Main Authors WAGLE, ASAVARI, PRASAD, SINGH, JAI, PAL
Format Patent
LanguageEnglish
French
Published 04.01.2001
Edition7
Subjects
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Summary:The present invention relates to pharmaceutical compositions and methods of treating neurological disorders. Compositions of the present invention comprise at least one hFGF-8 polypeptide, or at least one isolated nucleic acid, or its complement, encoding at least one hFGF-8 polypeptide. The present invention also includes hFGF-8 antibodies and chimerics, hFGF-8 expressing vectors, host cells and transgenics, as well as methods of making and using thereof. L'invention concerne des compositions pharmaceutiques et des procédés relatifs au traitement des troubles neurologiques. Les compositions considérées renferment au moins un polypeptide hFGF-8, ou au moins un acide nucléique isolé, ou son complément, qui code au moins un polypeptide hFGF-8. L'invention concerne également des anticorps et des chiméres hFGF-8, des vecteurs d'expression hFGF-8, des cellules hôtes et des animaux transgéniques, ainsi que des procédés relatifs à leur élaboration et à leur utilisation.
Bibliography:Application Number: WO2000US11885