NUEVOS COMPUESTOS INHIBIDORES DE LA FOSFODIESTERASA DEL TIPO 10A

Compuestos de la fórmula I, Donde R1, R2, R3, R4 y R5 se definen en las reivindicaciones y X es C-R6 o N, Y es CR7 o N, donde R6 y R7 son, entre otros, hidrógeno, halógeno, alcoxi, haloalcoxi y semejantes. The compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically...

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Bibliographic Details
Main Authors DRESCHER KARLA, HERVÉ GENESTE, OCHSE MICHAEL, JAKOB CLARISSA
Format Patent
LanguageSpanish
Published 31.03.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compuestos de la fórmula I, Donde R1, R2, R3, R4 y R5 se definen en las reivindicaciones y X es C-R6 o N, Y es CR7 o N, donde R6 y R7 son, entre otros, hidrógeno, halógeno, alcoxi, haloalcoxi y semejantes. The compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof are inhibitors of phosphodiesterase type 10A and to their use for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.
Bibliography:Application Number: UY20130034980