Macrocyclic inhibitors of flaviviridae viruses

Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.

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Bibliographic Details
Main Authors Schrier, Adam James, Highton, Adrian John, Aciro, Caroline, Steadman, Victoria Alexandra, Chiva, Jean Yves, Dunbar, Neil Andrew, Mackman, Richard, Poullennec, Karine G, Lazarides, Linos, Karki, Kapil Kumar, Jansa, Petr, Keats, Andrew John, Pettit, Simon Neil, Dean, David Kenneth, Siegel, Dustin Scott
Format Patent
LanguageEnglish
Published 02.04.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.
Bibliography:Application Number: US201715715080