Nucleic acid molecules encoding anti-P-selectin antibodies

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suff...

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Main Authors KLING DOROTHEE, STERN ANNE, KOPETZKI ERHARD, JANSEN-MOLENAAR MIRANDA, STUBENRAUCH KAY-GUNNAR, VAN DE WINKEL JAN, VAN VUGT MARTINE, STEINER BEAT, GRAUS YVO, REBERS FRANK, HIMBER JACQUES, BRAEMER PAMELA, PARREN PAUL
Format Patent
LanguageEnglish
Published 09.07.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).
Bibliography:Application Number: US201213471899