Anti-P-selectin antibodies

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suff...

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Main Authors KLING DOROTHEE, STERN ANNE, KOPETZKI ERHARD, STREIN PAMELA, JANSEN-MOLENAAR MIRANDA, STUBENRAUCH KAY-GUNNAR, VAN DE WINKEL JAN, VAN VUGT MARTINE, STEINER BEAT, GRAUS YVO, REBERS FRANK, HIMBER JACQUES, PARREN PAUL
Format Patent
LanguageEnglish
Published 07.08.2012
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).
Bibliography:Application Number: US201113187586