C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof

Disclosed are C-ring modified tricyclic benzonaphthiridinone compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, reg...

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Bibliographic Details
Main Authors Huck Bayard R, Sutton Amanda E, Richardson Thomas E, Karra Srinivasa R, Xiao Yufang
Format Patent
LanguageEnglish
Published 10.04.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed are C-ring modified tricyclic benzonaphthiridinone compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, regulation and/or modulation.
Bibliography:Application Number: US200913140090