Compositions and methods comprising sequences having meganuclease activity

Compositions and methods comprising polynucleotides and polypeptides having meganuclease activity are provided. Further provided are nucleic acid constructs, yeast, plants, plant cells, explants, seeds and grain having the meganuclease sequences. Various methods of employing the meganuclease sequenc...

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Main Authors Cigan Andrew Mark, Liu Lu, Young Joshua K, Ong Azalea, Svitashev Sergei, Falco Saverio Carl, Liu Zhan-Bin, Bermudez Ericka, English James, Gao Huirong
Format Patent
LanguageEnglish
Published 06.03.2018
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Summary:Compositions and methods comprising polynucleotides and polypeptides having meganuclease activity are provided. Further provided are nucleic acid constructs, yeast, plants, plant cells, explants, seeds and grain having the meganuclease sequences. Various methods of employing the meganuclease sequences are provided. Such methods include, for example, methods for producing a meganuclease with increased activity at a wide range of temperatures, methods for producing a yeast, plant, plant cell, explant or seed comprising a meganuclease with increased activity.
Bibliography:Application Number: US201615289993