Selective inhibitors for protein kinases and pharmaceutical composition and use thereof
The present invention provides a compound of formula (I) or the salt thereof: wherein R is at least one selected from the group consisting of unsubstituted C1-4 alkyl, C1-4 alkyl substituted by C6-18 aryl or -OR1, and -C( O)Z. The compound is a type-S protein kinase inhibitor, which binds to an ATP-...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | English |
Published |
22.08.2017
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides a compound of formula (I) or the salt thereof: wherein R is at least one selected from the group consisting of unsubstituted C1-4 alkyl, C1-4 alkyl substituted by C6-18 aryl or -OR1, and -C( O)Z. The compound is a type-S protein kinase inhibitor, which binds to an ATP-binding site and a substrate-recognition site of a protein kinase simultaneously. The present invention further provides a pharmaceutical composition, which includes a compound of formula (I) or a salt and a pharmaceutically acceptable carrier thereof. The present invention further provides a use of a compound of formula (I) or a salt thereof, which is for the manufacture of a protein kinase inhibitor as a drug. |
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Bibliography: | Application Number: US201514599349 |