Peripheral opioid receptor antagonists and uses thereof

The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound o...

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Bibliographic Details
Main Authors Fabian Steven R, Radebaugh Galen, Szeliga Jan, Zhang Huyi, Megati Sreenivasulu, Shah Syed M, Melucci Charles, Zhu Tianmin, Lokhnauth John, Patel Niketa, Ofslager Christian, Donato, III George Joseph, Bazhina Nataliya
Format Patent
LanguageEnglish
Published 08.08.2017
Subjects
BABY COMFORTERS
CHEMISTRY
CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES
DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR RECEIVING SPITTLE
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound of formula II-1:
Bibliography:Application Number: US201615276347