Macrocyclic urea and sulfamide derivatives as inhibitors of TAFIa

The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromb...

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Bibliographic Details
Main Authors Broenstrup Mark, Evers Andreas, Kallus Christopher, Globisch Anja, Schreuder Herman, Wagner Michael
Format Patent
LanguageEnglish
Published 27.06.2017
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Summary:The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromboses, embolisms, hypercoagulability or fibrotic changes.
Bibliography:Application Number: US201615057920