Triazolopyridyl compounds as aldosterone synthase inhibitors

This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprisin...

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Bibliographic Details
Main Authors Cai Jaiqiang, MacLean John, Ratcliffe Paul, Hoyt Scott B, Carswell Emma, London Clare, Taylor Jerry Andrew, Samanta Swapan Kumar, Xiong Yusheng, Cooke Andrew, Kulkarni Bheemashankar A, Bennett D. Jonathan
Format Patent
LanguageEnglish
Published 14.02.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
Bibliography:Application Number: US201514886563