Peripheral opioid receptor antagonists and uses thereof

The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound o...

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Main Authors Fabian Steven R, Radebaugh Galen, Szeliga Jan, Zhang Huyi, Megati Sreenivasulu, Shah Syed M, Melucci Charles, Zhu Tianmin, Lokhnauth John, Patel Niketa, Ofslager Christian, Donato, III George Joseph, Bazhina Nataliya
Format Patent
LanguageEnglish
Published 15.11.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound of formula II-1:
AbstractList The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound of formula II-1:
Author Melucci Charles
Radebaugh Galen
Fabian Steven R
Shah Syed M
Szeliga Jan
Lokhnauth John
Bazhina Nataliya
Patel Niketa
Ofslager Christian
Donato, III George Joseph
Zhang Huyi
Megati Sreenivasulu
Zhu Tianmin
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– fullname: Melucci Charles
– fullname: Zhu Tianmin
– fullname: Lokhnauth John
– fullname: Patel Niketa
– fullname: Ofslager Christian
– fullname: Donato, III George Joseph
– fullname: Bazhina Nataliya
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Wyeth LLC
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Snippet The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Peripheral opioid receptor antagonists and uses thereof
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