Peripheral opioid receptor antagonists and uses thereof

The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound o...

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Main Authors Fabian Steven R, Radebaugh Galen, Szeliga Jan, Zhang Huyi, Megati Sreenivasulu, Shah Syed M, Melucci Charles, Zhu Tianmin, Lokhnauth John, Patel Niketa, Ofslager Christian, Donato, III George Joseph, Bazhina Nataliya
Format Patent
LanguageEnglish
Published 15.11.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound of formula II-1:
Bibliography:Application Number: US201514870323