Method for producing contrast agent

A method for producing a contrast agent includes the reaction step of allowing a cyanine dye containing a naphthyl group and a carboxyl or carboxylate group to react with a polyethylene glycol containing an amino group in an organic solvent to form a conjugate, and the purification step of purifying...

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Bibliographic Details
Main Authors Tomatsu Fumiko, Takahashi Atsushi, Fukui Tatsuki, Sasaguri Daisuke
Format Patent
LanguageEnglish
Published 16.08.2016
Subjects
ADHESIVES
CHEMISTRY
DIAGNOSIS
DYES
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
LAKES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
MORDANTS
NATURAL RESINS
ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES
PAINTS
POLISHES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SURGERY
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Summary:A method for producing a contrast agent includes the reaction step of allowing a cyanine dye containing a naphthyl group and a carboxyl or carboxylate group to react with a polyethylene glycol containing an amino group in an organic solvent to form a conjugate, and the purification step of purifying the conjugate using an organic solvent.
Bibliography:Application Number: US201414534111