VHNAR anti-cytokine domains

The present invention concerns therapeutic compositions containing proteins that are the variable regions of IgNAR immunoglobulins, denominated vNAR, that specifically bind and neutralizes cytokines involved in a diversity of process such as inflammation and neovascularization, its ability to reach,...

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Main Authors Mata-González María Teresa, Licea-Navarro Alexei F, Sanchez-Castrejon Edna, García-Ubbelohde Walter J, Olguín-Jimenez Araceli, Paniagua-Solís Jorge F, Camacho-Villegas Tanya A
Format Patent
LanguageEnglish
Published 26.07.2016
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention concerns therapeutic compositions containing proteins that are the variable regions of IgNAR immunoglobulins, denominated vNAR, that specifically bind and neutralizes cytokines involved in a diversity of process such as inflammation and neovascularization, its ability to reach, bind, and neutralize the activity of one antigenic molecule localized in an immunoprivileged organs, are also described.
Bibliography:Application Number: US201313944522