Single chain relaxin polypeptides

• Main Authors: GUNDLACH ANDREW LAWRENCE, WADE JOHN DESMOND, BATHGATE ROSS ALEXANDER DAVID, HAUGAARD-KEDSTROM LINDA MARIA, ROSENGREN KARL JOHAN, HOSSAIN MOHAMMED AKHTER, LAWRENCE ANDREW J
• Format: Patent
• Language: English
• Published: 07.06.2016
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SUGARS

The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are anta...