Nitrogen-containing bicyclic aromatic heterocyclic compound

[Problem] On the basis of a cathepsin S inhibitory effect, an excellent agent for treating or preventing autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like is provided. [Means for Solution] It was found that a nitrogen-...

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Main Authors SATO JUNJI, AOYAMA NAOHIRO, NAKAJIMA YUTAKA, IMADA SUNAO, NAKANISHI KEITA, NIGAWARA TAKAHIRO, SHIRAI FUMIYUKI, SHIRAKAMI SHOHEI, KUBO KAORI, TAKASUNA YUJI
Format Patent
LanguageEnglish
Published 03.05.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:[Problem] On the basis of a cathepsin S inhibitory effect, an excellent agent for treating or preventing autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like is provided. [Means for Solution] It was found that a nitrogen-containing bicyclic heterocyclic compound has the excellent cathepsin S inhibitory effect, thereby completing the invention. The compound of the present invention has the cathepsin S inhibitory effect, and can be used as an agent for preventing and/or treating autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like.
Bibliography:Application Number: US201314394373