5H-cyclopenta[d]pyrimidines as AKT protein kinase inhibitors

Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pat...

Full description

Saved in:
Bibliographic Details
Main Authors MITCHELL IAN S, HENTEMANN MARTIN F, SCHLACHTER STEPHEN T, XU RUI, BENCSIK JOSEF R, WALLACE ELI M, LEIVERS ANNA, LIANG JUN, KALLAN NICHOLAS C, TANG TONY P, BLAKE JAMES F
Format Patent
LanguageEnglish
Published 03.05.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
Bibliography:Application Number: US201414523481