Macrocyclic compounds for modulating IL-17

The invention relates generally to macrocyclic compounds of formula I and their therapeutic use. More particularly, the invention relates to macrocyclic compounds that modulate the activity of IL-17 and/or are useful in the treatment of medical conditions, such as inflammatory diseases and other IL-...

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Main Authors SEIGAL BENJAMIN A, TERRETT NICHOLAS K, THORARENSEN ATLI, TAYLOR MICHAEL, BRIGGS TIMOTHY F, SHORTSLEEVES KELLEY C, SNEDEKER CHERI, CONNORS WILLIAM H, ALEXANDER SETHU L, HALE STEPHEN P, YAN DINGXUE, FAVALORO, JR. FRANK G, CIPRIANI TYLER J, XING LI
Format Patent
LanguageEnglish
Published 15.03.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates generally to macrocyclic compounds of formula I and their therapeutic use. More particularly, the invention relates to macrocyclic compounds that modulate the activity of IL-17 and/or are useful in the treatment of medical conditions, such as inflammatory diseases and other IL-17-associated disorders.
Bibliography:Application Number: US201314376247