B cell maturation antigen (BCMA) binding proteins

The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening a...

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Main Authors CLEGG STEPHANIE JANE, CRAIGEN JENNIFER L, WATTAM TREVOR ANTHONY KENNETH, PARMAR RADHA SHAH, ALGATE PAUL, MAYES PATRICK, LEWIS ALAN PETER, HAMBLIN PAUL ANDREW
Format Patent
LanguageEnglish
Published 01.03.2016
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
AbstractList The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
Author HAMBLIN PAUL ANDREW
CLEGG STEPHANIE JANE
LEWIS ALAN PETER
ALGATE PAUL
PARMAR RADHA SHAH
WATTAM TREVOR ANTHONY KENNETH
CRAIGEN JENNIFER L
MAYES PATRICK
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– fullname: PARMAR RADHA SHAH
– fullname: ALGATE PAUL
– fullname: MAYES PATRICK
– fullname: LEWIS ALAN PETER
– fullname: HAMBLIN PAUL ANDREW
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Snippet The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title B cell maturation antigen (BCMA) binding proteins
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