B cell maturation antigen (BCMA) binding proteins

The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening a...

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Bibliographic Details
Main Authors CLEGG STEPHANIE JANE, CRAIGEN JENNIFER L, WATTAM TREVOR ANTHONY KENNETH, PARMAR RADHA SHAH, ALGATE PAUL, MAYES PATRICK, LEWIS ALAN PETER, HAMBLIN PAUL ANDREW
Format Patent
LanguageEnglish
Published 01.03.2016
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
Bibliography:Application Number: US201313795314