Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.

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Bibliographic Details
Main Authors TAO ZHI-FU, JUDD ANDREW, HANSEN TODD M, WANG LE, SONG XIAOHONG, DOHERTY GEORGE, SOUERS ANDREW, BRUNCKO MILAN, SULLIVAN GERARD M, WANG XILU, FREY ROBIN, WENDT MICHAEL D, KUNZER AARON R
Format Patent
LanguageEnglish
Published 23.02.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
Bibliography:Application Number: US201414559828