Antibodies to FeRn and uses thereof

This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.

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Bibliographic Details
Main Authors LIU LIMING, SATO AARON K, TENHOOR CHRISTOPHER, LADNER ROBERT CHARLES, MCGIVNEY JAMES, DUMONT JENNIFER, MURUGANANDAM ARUMUGAM, BITONTI ALAN J, VISWANATHAN MALINI, WOOD CLIVE, MCDONNELL KEVIN
Format Patent
LanguageEnglish
Published 16.02.2016
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Summary:This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
Bibliography:Application Number: US201414168839