Activity based probes (ABPs) interacting with glycosidases
An activity based probe (ABP) comprising a glycosidase inhibitor, and a detection-group. The ABPs of the inventions are used for diagnosing storage disorder for screening of compounds suitable for preventing and/or treating a storage disorder, for monitoring of therapeutic enzymes for lysosomal stor...
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
16.06.2015
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Subjects | |
Online Access | Get full text |
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Summary: | An activity based probe (ABP) comprising a glycosidase inhibitor, and a detection-group. The ABPs of the inventions are used for diagnosing storage disorder for screening of compounds suitable for preventing and/or treating a storage disorder, for monitoring of therapeutic enzymes for lysosomal storage disorders, and for ultra-sensitive visualization of glycosidase-fusion proteins in molecular imaging. |
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Bibliography: | Application Number: US201113583193 |