Non-pegylated long-circulating liposomes
The present invention provides a long circulating non-pegylated liposomal doxorubicin hydrochloride composition for parenteral administration and a process for its preparation. The circulation time in Swiss albino mice is at least 25 times longer than conventional non-liposomal formulations. The non...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
17.03.2015
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides a long circulating non-pegylated liposomal doxorubicin hydrochloride composition for parenteral administration and a process for its preparation. The circulation time in Swiss albino mice is at least 25 times longer than conventional non-liposomal formulations. The non-pegylated liposomes are stable, exhibit low toxicity and have been found to be efficacious in different tumor models. |
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Bibliography: | Application Number: US20030748094 |