Isotope preparation method

The present invention provides a method for the generation of 223Ra of pharmaceutically tolerable purity comprising i) preparing a generator mixture comprising 227Ac, 227Th and 223Ra; ii) loading said generator mixture onto a strong base anion exchange resin; iii) eluting said 223Ra from said strong...

Full description

Saved in:
Bibliographic Details
Main Authors BØRRETZEN PEER, KARLSON JAN ROGER
Format Patent
LanguageEnglish
Published 06.01.2015
Subjects
CHEMISTRY
COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM,CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THERARE-EARTH METALS
CONVERSION OF CHEMICAL ELEMENTS
HUMAN NECESSITIES
HYGIENE
INORGANIC CHEMISTRY
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEAR ENGINEERING
NUCLEAR PHYSICS
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
RADIOACTIVE SOURCES
Online AccessGet full text

Cover

More Information
Summary:The present invention provides a method for the generation of 223Ra of pharmaceutically tolerable purity comprising i) preparing a generator mixture comprising 227Ac, 227Th and 223Ra; ii) loading said generator mixture onto a strong base anion exchange resin; iii) eluting said 223Ra from said strong base anion exchange resin using a first mineral acid in an alcoholic aqueous solution to give a first eluted 223Ra solution; iv) loading the 223Ra of the first eluted 223Ra solution onto a strong acid cation exchange resin; and v) eluting the 223Ra from said strong acid cation exchange resin using a second mineral acid in aqueous solution to provide a second eluted solution. The invention additionally provides products of corresponding purity and/or products obtained or obtainable by such a method.
Bibliography:Application Number: US201113695353