Heterocyclic compounds and uses thereof

New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase m...

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Main Authors ZHANG QIONG, POON DANIEL, HUANG ZILIN, RENHOWE PAUL A, SMITH AARON, MACHAJEWSKI TIMOTHY, MCKENNA MAUREEN, SENDZIK MARTIN, ANTONIOS-MCCREA WILLIAM R, JIN JEFF, XU YONGJIN, SHAFER CYNTHIA, CHEN ZHENG
Format Patent
LanguageEnglish
Published 21.10.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
Bibliography:Application Number: US201213396339