Heterocyclic compound, and composition for treating inflammatory diseases using same

Provided are heterocyclic compounds, having effects of treating and preventing inflammatory diseases and treating skin wounds, and particularly, exhibiting effects of recovering disrupted skin barriers, mitigating inflammation, and pruritus. Also, a composition containing the compound as an effectiv...

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Main Authors GWAK HYUNG SUB, PARK TAE KYO, JEON JEONG EUN, LEE DAE YON, KIM UK IL, YUN JOUNG YUL, LEE HYANG SOOK, WOO SUNG HO, JEONG SE KYOO, KIM YONG ZU, PARK BYEONG DEOG, CHOI HYUNG MOOK
Format Patent
LanguageEnglish
Published 19.08.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Summary:Provided are heterocyclic compounds, having effects of treating and preventing inflammatory diseases and treating skin wounds, and particularly, exhibiting effects of recovering disrupted skin barriers, mitigating inflammation, and pruritus. Also, a composition containing the compound as an effective component can be used to mitigate various inflammatory diseases and protease activated receptor-2 (PAR-2)-overexpressed diseases, and can be particularly used as a composition having an anti-inflammatory function in inflammatory skin diseases including atopic dermatitis and the like, by inhibiting PAR-2 activity.
Bibliography:Application Number: US201113818355