Dicarboxylic acid derivatives as S1P1 receptor agonists

The present invention relates to new compounds of formula (I) possessing agonistic activity at sphingosine-1-phosphate (S1P) receptors, their process of preparation and their use as immunosuppressive agents. The invention is also directed to pharmaceutical compositions containing these compounds and...

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Main Authors BERREBI-BERTRAND ISABELLE, THENNATI RAJAMANNAR, SAMANTA BISWAJIT, ROBERT PHILIPPE, ARADHYE JAYRAJ DILIPBHAI, SCHWARTZ JEANARLES, PANCHAL BHAVESH MOHANBHAI, JIVANI JIGNESH KANTILAL, LEVOIN NICOLAS, PAL RANJAN KUMAR, LECOMTE JEANNE-MARIE, CAPET MARC, PILLAI MUTHUKUMARAN NATARAJAN
Format Patent
LanguageEnglish
Published 19.08.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to new compounds of formula (I) possessing agonistic activity at sphingosine-1-phosphate (S1P) receptors, their process of preparation and their use as immunosuppressive agents. The invention is also directed to pharmaceutical compositions containing these compounds and use of these compounds for treatment/prevention of immune mediated diseases and conditions or inflammatory diseases and conditions.
Bibliography:Application Number: US20080664718