Adenoviral vector-based malaria vaccines

The invention provides adenoviral vectors comprising an adenoviral genome comprising heterologous antigen-encoding nucleic acid sequences, such as Plasmodium nucleic acid sequences, operably linked to promoters. The invention further provides a method of inducing an immune response against malaria i...

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Bibliographic Details
Main Authors KING C. RICHTER, KOVESDI IMRE, MCVEY DUNCAN L, CARUCCI DANIEL JOHN, ETTYREDDY DAMODAR R, DOOLAN DENISE LOUISE, BRUDER JOSEPH T
Format Patent
LanguageEnglish
Published 01.07.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides adenoviral vectors comprising an adenoviral genome comprising heterologous antigen-encoding nucleic acid sequences, such as Plasmodium nucleic acid sequences, operably linked to promoters. The invention further provides a method of inducing an immune response against malaria in a mammal comprising administering the adenoviral vectors to the mammal.
Bibliography:Application Number: US20060064554