FGF21 conjugates and anti-diabetic uses thereof

The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diab...

Full description

Saved in:
Bibliographic Details
Main Authors VIOLAND BERNARD NORMAN, LEVIN NANCY JANE, DAS TAPAN KANTI, PARSONS ERIN KRISTEN, ISHINO TETSUYA, HODGE TAMARA SHAFER, PALANKI MOORTHY SITHARAMAIAH SURIYANARAYANA
Format Patent
LanguageEnglish
Published 13.05.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
Bibliography:Application Number: US201113289533