Imidazole carbonyl compound

An antibiotic compound having a novel mechanism of action, weak cytotoxicity, high solubility in water, effective in inhibiting both DNA gyrase GyrB and topoisomerase IV ParE subunits, and having antibacterial activity.

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Bibliographic Details
Main Authors SONEDA TSUYOSHI, ACHIWA ISSEI, YOKOMIZO AKI, KONOSU TOSHIYUKI, HOSOKAWA TAKAFUMI, KUROYANAGI JUNICHI, YAMAMOTO YUKO, UCHIDA TAKUYA, FUJISAWA TETSUNORI, TAKESHITA HIROSHI, NOGUCHI TETSUJI, MASUDA NOBUHISA, KAGOSHIMA YOSHIKO
Format Patent
LanguageEnglish
Published 17.09.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:An antibiotic compound having a novel mechanism of action, weak cytotoxicity, high solubility in water, effective in inhibiting both DNA gyrase GyrB and topoisomerase IV ParE subunits, and having antibacterial activity.
Bibliography:Application Number: US20080811004