Fused pyridine and pyrazine derivatives as kinase inhibitors

A series of amino-substituted fused pyridine and pyrazine derivatives, in particular amino-substituted quinoline and quinoxaline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovasc...

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Main Authors MACDONALD JONATHAN DAVID, ALLEN DANIEL REES, SHARPE ANDREW, BROWN JULIEN ALISTAIR, SAVILLE-STONES ELIZABETH ANNE, BURLI ROLAND, HAUGHAN ALAN FINDLAY
Format Patent
LanguageEnglish
Published 20.08.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A series of amino-substituted fused pyridine and pyrazine derivatives, in particular amino-substituted quinoline and quinoxaline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
Bibliography:Application Number: US201013201160