Isoxazole compounds as inhibitors of heat shock proteins

Isoxazoles of formula (A) or (B) wherein R1 is a group of formula (IB) The isoxazoles are inhibitors of HSP90 activity, and useful for the treatment of, for example, cancers.

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Bibliographic Details
Main Authors DRYSDALE MARTIN JAMES, MCDONALD EDWARD, FINCH HARRY, CHEUNG KWAI MING, DYMOCK BRIAN WILLIAM, MATTHEWS THOMAS PETER, JAMES KAREN ELIZABETH, WEBB PAUL
Format Patent
LanguageEnglish
Published 28.05.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Isoxazoles of formula (A) or (B) wherein R1 is a group of formula (IB) The isoxazoles are inhibitors of HSP90 activity, and useful for the treatment of, for example, cancers.
Bibliography:Application Number: US201213525409