Pyridazinone compounds and P2X7 receptor inhibitors

Novel pyridazinone compounds of formula (I), which inhibit the purinergic P2X7 receptor and are useful for prevention, therapy and improvement of inflammatory and immunological diseases.

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Bibliographic Details
Main Authors SHIGETA YUKIHIRO, IO MEGUMI, WATANABE TSUNEO, TAKEUCHI KAZUYA, SHINTANI YUSUKE, NAGAI HIROSHI, KAMON JUNJI, HORIKAWA MASATO, NAGAE KEI, HIROKAWA YUTAKA
Format Patent
LanguageEnglish
Published 14.05.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel pyridazinone compounds of formula (I), which inhibit the purinergic P2X7 receptor and are useful for prevention, therapy and improvement of inflammatory and immunological diseases.
Bibliography:Application Number: US20080680689