Method for prediction of sensitivity to 5-fluorouracil-type anticancer agent

A factor affecting sensitivities to anticancer agents is analyzed and the validity of the factor is demonstrated. The present invention provides a method for predicting sensitivities to 5-fluorouracil-based anticancer agents using the copy number of dihydropyrimidine dehydrogenase gene as an indicat...

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Bibliographic Details
Main Authors OOYAMA AKIO, KOBUNAI TAKASHI
Format Patent
LanguageEnglish
Published 14.05.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:A factor affecting sensitivities to anticancer agents is analyzed and the validity of the factor is demonstrated. The present invention provides a method for predicting sensitivities to 5-fluorouracil-based anticancer agents using the copy number of dihydropyrimidine dehydrogenase gene as an indicator. Also disclosed are a kit and primers for use in predicting sensitivities to 5-fluorouracil-based anticancer agents.
Bibliography:Application Number: US20070161957