Thermoprotected compositions and process for terminal steam sterilization of microparticle preparations
Compositions of submicron- to micron-sized particles of water-insoluble biologically active substances that are stabilized by thermoprotecting agents, can be terminally steam sterilized without any significant increase of mean particle size. These compositions display markedly reduced heat-induced c...
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Main Author | |
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Format | Patent |
Language | English |
Published |
09.04.2013
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Subjects | |
Online Access | Get full text |
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Summary: | Compositions of submicron- to micron-sized particles of water-insoluble biologically active substances that are stabilized by thermoprotecting agents, can be terminally steam sterilized without any significant increase of mean particle size. These compositions display markedly reduced heat-induced coagulation, flocculation, or particle size growth during the terminal steam sterilization process. |
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Bibliography: | Application Number: US19990321766 |