Pyrimidine inhibitors of kinase activity

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said...

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Main Authors BELL RANDY L, MANTEI ROBERT A, WANG GARY T, BA-MAUNG NWE Y, FIDANZE STEVE D, SHEPPARD GEORGE S, SORENSEN BRYAN K, ERICKSON SCOTT A, CLARK RICHARD F, WANG JIEYI
Format Patent
LanguageEnglish
Published 15.01.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R.
Bibliography:Application Number: US20100788008