Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders

Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity.

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Main Authors FRY PETER TIMOTHY, DUPREE TOM BANKSIA, STEWART ALAN JOHN, BRADLEY STUART EDWARD, SAMBROOK-SMITH COLIN PETER, PROCTER MARTIN JAMES, SMYTH DONALD, HANRAHAN PATRICK ERIC, BLOXHAM JASON, SCHOFIELD KAREN LESLEY, KRULLE THOMAS MARTIN
Format Patent
LanguageEnglish
Published 02.10.2012
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Summary:Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity.
Bibliography:Application Number: US20080601100