JAK-2 modulators and methods of use
This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibit...
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Format | Patent |
Language | English |
Published |
03.01.2012
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Abstract | This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention. |
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AbstractList | This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention. |
Author | CHEN JEFF DU HONGWANG TAKEUCHI CRAIG STACY MANN GRACE FORSYTH TIMOTHY KEARNEY PATRICK LEAHY JAMES W ZHOU PEIWEN HUYNH TAI PHAT RIDGWAY BRIAN HUGH LEE MATTHEW SANGYUP GALAN ADAM ANTONI JOHNSON HENRY WILLIAM BEECROFT |
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Title | JAK-2 modulators and methods of use |
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