JAK-2 modulators and methods of use

This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibit...

Full description

Saved in:
Bibliographic Details
Main Authors TAKEUCHI CRAIG STACY, JOHNSON HENRY WILLIAM BEECROFT, GALAN ADAM ANTONI, KEARNEY PATRICK, MANN GRACE, FORSYTH TIMOTHY, ZHOU PEIWEN, LEAHY JAMES W, CHEN JEFF, DU HONGWANG, HUYNH TAI PHAT, RIDGWAY BRIAN HUGH, LEE MATTHEW SANGYUP
Format Patent
LanguageEnglish
Published 03.01.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention.
Bibliography:Application Number: US20070443103