Reduction of imiquimod impurities in pharmaceutical creams

Pharmaceutical formulations and methods including an immune response modifier (IRM) compound and an oleic acid component are provided where stability is improved by using oleic acid have low polar impurities such as peroxides.

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Bibliographic Details
Main Authors NELSON ROBERT J, STATHAM ALEXIS S
Format Patent
LanguageEnglish
Published 19.04.2011
Subjects
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Summary:Pharmaceutical formulations and methods including an immune response modifier (IRM) compound and an oleic acid component are provided where stability is improved by using oleic acid have low polar impurities such as peroxides.
Bibliography:Application Number: US20100698113