Process for the preparation of cabergoline

A process for preparing cabergoline (I) from ergoline-8 -carboxylic acid ester (XIII) comprising the following steps. (XIII), (XVI), (XVII), (XVIII), (XIX), (I). The present case also relates to the intermediates (XVI), (XVII), (XVIII) and (XIX) as well as the polymorphic amorphous form of Cabergoli...

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Main Authors BALINT SANDORNE, IGNACZNE SZENDREI GYORGYI, DEMETER ADAM, GALAMBOS JANOS, CZIBULA LASZLO, KASSAI FERENCNE, SEBOEK FERENC
Format Patent
LanguageEnglish
Published 28.12.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A process for preparing cabergoline (I) from ergoline-8 -carboxylic acid ester (XIII) comprising the following steps. (XIII), (XVI), (XVII), (XVIII), (XIX), (I). The present case also relates to the intermediates (XVI), (XVII), (XVIII) and (XIX) as well as the polymorphic amorphous form of Cabergoline (I) and the production thereof.
Bibliography:Application Number: US20050591202