Method for producing solid galenic formulations using a crosslinked non-thermoplastic carrier

The invention concerns a method for producing solid galenic formulations which consists in: forming a processable paste comprising a) 50 to 99.4 wt. % of at least one non-thermoplastic carrier, b) 0.5 to 30 wt. % of at least an adjuvant selected among thermoplastic polymers, lipids, sugar alcohols a...

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Bibliographic Details
Main Authors BERNDL GUNTHER, MAGERLEIN MARKUS, ROSENBERG JOERG
Format Patent
LanguageEnglish
Published 07.12.2010
Subjects
HUMAN NECESSITIES
HYGIENE
MANUFACTURE BY DRY PROCESSES OF ARTICLES, WITH OR WITHOUTORGANIC BINDING AGENTS, MADE FROM PARTICLES OR FIBRES CONSISTINGOF WOOD OR OTHER LIGNOCELLULOSIC OR LIKE ORGANIC MATERIAL
MEDICAL OR VETERINARY SCIENCE
NAILING OR STAPLING MACHINES IN GENERAL
PERFORMING OPERATIONS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TRANSPORTING
WORKING OR PRESERVING WOOD OR SIMILAR MATERIAL
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Summary:The invention concerns a method for producing solid galenic formulations which consists in: forming a processable paste comprising a) 50 to 99.4 wt. % of at least one non-thermoplastic carrier, b) 0.5 to 30 wt. % of at least an adjuvant selected among thermoplastic polymers, lipids, sugar alcohols and solubilizing agents, c) 0.1 to 49.5 wt. % of at least one active principle, at a temperature not less than the softening temperature of the adjuvant but rising to at least 70° C.; then in cooling the resulting paste. Said solid galenic formulations quickly disintegrate in an aqueous medium.
Bibliography:Application Number: US20050530483