Crystals of whole antibodies and fragments thereof and methods for making and using them

This invention relates to crystals of whole antibodies and fragments thereof, and formulations and compositions comprising such crystals. More particularly, methods are provided for the crystallization of high concentrations of whole antibodies, and fragments thereof, in large batches, and for the p...

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Bibliographic Details
Main Authors SHENOY BHAMI, YANG MARK X, MARGOLIN ALEXEY L, GOVARDHAN CHANDRIKA P
Format Patent
LanguageEnglish
Published 16.11.2010
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Summary:This invention relates to crystals of whole antibodies and fragments thereof, and formulations and compositions comprising such crystals. More particularly, methods are provided for the crystallization of high concentrations of whole antibodies, and fragments thereof, in large batches, and for the preparation of stabilized whole antibody crystals for use alone, or in dry or slurry formulations or compositions. This invention also relates to methods for stabilization, storage and delivery of biologically active whole antibody crystals.
Bibliography:Application Number: US20010034950