Image analysis

A method for the automated analysis of digital images, particularly for the purpose of assessing nuclear pleomorphism from images of histological slides for prognostication of breast cancer. The method includes the steps of identifying the locations of objects within the image which have intensity a...

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Bibliographic Details
Main Authors WATSON GRAHAM HOWARD, WATSON SHARON KATRINA
Format Patent
LanguageEnglish
Published 23.03.2010
Subjects
CALCULATING
COMPUTING
COUNTING
HANDLING RECORD CARRIERS
PHYSICS
PRESENTATION OF DATA
RECOGNITION OF DATA
RECORD CARRIERS
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Summary:A method for the automated analysis of digital images, particularly for the purpose of assessing nuclear pleomorphism from images of histological slides for prognostication of breast cancer. The method includes the steps of identifying the locations of objects within the image which have intensity and size characteristics consistent with epithelial cell nuclei and deriving boundaries for those objects. Statistics concerning at least the shapes of the derived boundaries are calculated and clutter is rejected on the basis of those statistics and/or they are used to assign probabilities that the respective objects are epithelial cell nuclei, and a measure of the variability of at least the areas enclosed by such boundaries is then calculated.
Bibliography:Application Number: US20050543911